Variation of Glycyrrhizin and Liquiritin Contents within a Population of 5-Year-Old Licorice (Glycyrrhiza uralensis) Plants Cultivated under the Same Conditions

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Characterization of a glycyrrhizin-deficient strain of Glycyrrhiza uralensis.

A triterpene saponin, glucoglycyrrhizin, was isolated from a glycyrrhizin-deficient strain 83-555 of Glycyrrhiza uralensis (Leguminosae), and the structure was determined by chemical and spectral data to be 3-O-[β-D-glucopyranosyl-(1→2)-β-D-glucuronopyranosyl]-glycyrrhetinic acid. Since this saponin has a 2'-O-β-D-glucopyranosyl moiety instead of the 2'-O-β-D-glucuronopyranosyl moiety of glycyr...

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Biol. Pharm. Bull. 28(6) 1113—1116 (2005)

been important crude drugs worldwide for at least 4000 years, and the major sweet constituent, glycyrrhizin, is not only a well-recognized natural sweetener but also a pharmaceutical with antiinflammatory and hepatoprotective activities. In addition, licorice is the most frequently used component in Chinese and Japanese traditional medicines, and the roots and stolons of Glycyrrhiza uralensis F...

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The constituents of licorice (Glycyrrhiza uralensis) differentially suppress nitric oxide production in interleukin-1β-treated hepatocytes

Licorice (Glycyrrhizae radix) is the roots and stolons of Glycyrrhiza uralensis Fischer or Glycyrrhiza glabra Linnaeus in the Japanese Pharmacopoeia. Glycyrrhizae radix has been widely used as a sweetener and a traditional medicine. A Glycyrrhizae radix extract contains many constituents and has antispasmodic, antitussive, anti-ulcer, and anti-inflammatory effects. However, reports comparing th...

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Hepatoprotective effect of licorice, the root of Glycyrrhiza uralensis Fischer, in alcohol-induced fatty liver disease

BACKGROUND Our previous study suggested that licorice has anti-inflammatory activity in lipopolysaccharide-stimulated microglial cells and anti-oxidative activity in tert-butyl hydroperoxide-induced oxidative liver damage. In this study, we evaluated the effect of licorice on chronic alcohol-induced fatty liver injury mediated by inflammation and oxidative stress. METHODS Raw licorice was ext...

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ژورنال

عنوان ژورنال: Biological and Pharmaceutical Bulletin

سال: 2011

ISSN: 0918-6158,1347-5215

DOI: 10.1248/bpb.34.1334